Looking for online definition of cementifying fibroma in the Medical Dictionary? cementifying fibroma explanation free. What is cementifying fibroma? Meaning of . The term “cementifying fibroma” was originally applied to the lesion of the mandibular incisor teeth now referred to as “periapical cemental dysplasia” ( Pindborg. Cemento-ossifying fibroma (COF) are rare, benign neoplasms that usually arise from the mandible or maxilla. They most often arise from the tooth bearing areas .

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Cemento-ossifying fibromas are usually well-circumscribed masses which expand the underlying bone. This website is intended for pathologists and laboratory personnel, who understand that medical information is imperfect and must be interpreted using reasonable medical judgment.

Cemento-ossifying fibroma with mandibular fracture. The latter manifests as a well delimited unilocular lesion containing variable amounts of radio-opaque material. Author information Article notes Copyright and License information Disclaimer. Other authors, however, advocate more extensive surgery for fibgoma aggressive lesions and lesions involving craniofacial bones in light of the potential for recurrence.

Pathology Outlines – Ossifying fibroma

The tumor was removed under local anesthesia and the excised specimen measured Images hosted on other servers: Irregular trabeculae of lamellar bone are also evident. Cementifying fibroma is round in shape and causes nodular or dome shaped jaw finroma while fibrous dysplasia is rectangular and causes elongated fusiform expansion.


The orthopantomogram revealed the presence of well-defined radiolucency in 24, 25, 26, 27 regions figure 2 B. Histological analysis showed a cellular fibroblastic tissue characterized by bundles of collagen densely packed and proliferating fibroblasts.

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A thin radiolucent line representing a fibrous capsule may separate it from surrounding bone. The margins of the lesion appeared to be well-defined.

Computed tomography CT scan showed expansion of the buccal and lingual cortical plates of the mandible [ Figure 3 ]. The maxillary cross-sectional occlusal radiograph demonstrated a round-shaped well-defined radiolucent lesion extending from 24 to 27 region. Chondrosarcoma or osteosarcoma, fibrous dysplasia, odontogenic cysts, squamous cell carcinomas, calcifying odontogenic cysts Gorlin cystsand calcifying epithelial odontogenic tumors Pindborg tumors.

Takakazu et al 8 conducted a clinical roentgenographic analysis of eight cases of cementifying fibroma and observed that out of eight, three demonstrated cystic radiographic appearance, four revealed fibroa radiographic appearance while foffy appearance was seen in only one patient.

Another interesting feature is the centrifugal growth pattern rather than linear, so the lesion grows by expansion equally in all direction and presents a round mass cenentifying seen in our patient. Patient also had a history of pus discharge from left ear, which resolved spontaneously.

The overlying mucosa was normal in appearance.

Open in a separate window. Cementifyong views in Author information Copyright and License information Disclaimer. The differential is essentially that of a lesion of the mandible or lesion of the maxilla depending on location and degree of mineralisation. A clinicopathologic stidy of sixty-four cases.


The postoperative follow up was favorable, and 1 year later the patient reported no discomfort in the area. Mandibular central cemento-ossifying fibromas usually shell out easily at surgery, but maxillary central cemento-ossifying fibromas are more difficult to remove completely than mandibular central cemento-ossifying fibromas. The patient mentioned that the mass had first appeared 3 months ago and became slightly larger since then.

Conservative surgery is therefore recommended even if the tumour is large with bowing and erosion of the inferior border of the mandible and radical treatment of the tumour such as an en bloc resection should only be considered if there are recurrences cementifjing to its aggressive nature. However, Eversole and his co-workers in a study of 64 cases of cemento-ossifying fibroma reported a recurrence rate of as high as 28 per cent following surgical curettage of these lesions.

J Radiol Case Rep.

They are thought to arise from the periodontal ligament, accounting for the usual vicinity to teeth 3. Cementifying fibroma has a wide age range from 7—58 years while the mean age in fibrous dysplasia is 20 years.

Benign fibro-osseous jaw lesions of periodontal membrane origin: An analysis of cases.